News
Antibiotic resistance: more than 39 million deaths expected by 2050, according to a GBD Project analysis published in The Lancet
By Sara Moraca A new study published in The Lancet predicts that more than 39 million people could die from antibiotic-resistant infections by 2050. This research, conducted by the Global Research on Antimicrobial Resistance (GRAM) Project, represents the first in-depth global analysis of antimicrobial resistance (AMR) trends between 1990 and 2021 and their projections through mid-century. The study examined 204 countries and territories, drawing a troubling picture for the future of global...
Estimates of antibiotic resistance in Italy and Western Europe in 2019: a comparative analysis based on MICROBE
By 2050, it is estimated that antimicrobial resistance (AMR) will cause 10 million annual deaths worldwide, costing up to $100 trillion. Antibiotic resistance (ABR) is the most significant health threat and, in 2019, caused 1.27 million deaths globally. One in 5 deaths occurred under five years of age, and 6 bacterial pathogens accounted for more than 70% of deaths. Our objective was to compare mortality and disability estimates (DALYs) associated with ABR in 2019 in Italy and Western Europe...
The Burden of Type 1 and 2 Diabetes among adolescents and young adults in 24 Western European countries, 1990-2019
As little is known about the burden of type 1 (T1DM) and type 2 diabetes (T2DM) in adolescents in Western Europe (WE), we aimed to explore their epidemiology among 10-24 year-olds. Estimates were retrieved from the Global Burden of Diseases Study (GBD) 2019. We reported counts, rates per 100,000 population, and percentage changes from 1990 to 2019 for prevalence, incidence and years lived with disability (YLDs) of T1DM and T2DM, and the burden of T2DM in YLDs attributable to high body mass...
Measures of the burden of type 2 diabetes in Italy assessed using AMD data over 12 years
Patients with type 2 diabetes mellitus (T2DM) are rapidly increasing in Italy due to aging, preventable risk factors, and a worsening socioeconomic environment. T2DM and its consequences take a heavy toll on health care systems and the economy, given the costly management, difficulties in coping with daily life, and decreased productivity of patients/workers. Considering the long life expectancy in Italy and a decreasing mortality rate due to T2DM, this study aims to calculate the years lived...
The “burden” of Hepatitis B & C in Europe: analysis by CESP of Milano-Bicocca University on GBD 2019 estimates
In 2016, the World Health Assembly adopted the resolution to eliminate viral hepatitis by 2030. A GBD study led by the University of Milan-Bicocca, published in the journal The Lancet Public Health, aimed to provide an overview of the impact of hepatitis B virus (HBV) and hepatitis C virus (HCV) in Europe and their changes from 2010 to 2019 using estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 and highlighted what strategies to put in place to move...
Air pollution and health in Italy: analysis of time trends 1990-2019 from GBD 2019 estimates
Air pollution is one of the risk factors assessed by the Global Burden of Disease Study and is of great importance in population health. It actually ranks fourth in terms of impact on a global scale. Since it is known that air quality in Italy has peculiar criticalities, especially in the Po Valley area, we evaluated how the impact estimated by the GBD for our peninsula has varied over time, from 1990 to 2019, with regard to two specific pollutants: atmospheric particulate matter ≤2.5μm...
How to arrive prepared for future pandemics?
In a recent episode of IHME's "Global Health Insights," Joseph Dieleman, professor of Health Metrics Sciences at IHME, and Thomas Bollyky, director of the Council on Foreign Relations (CFR) Global Health program, discuss how to arrive prepared for the next pandemic. The conversation revolves around the findings of an article published in The Lancet, which explores possible contextual factors associated with variability in COVID-19 infection and mortality in the different countries observed....
Redistribution of garbage codes to underlying causes of death: a systematic analysis on Italy and a comparison with the most populous Western European countries based on the Global Burden of Disease Study 2019
One of the main tasks of our network is to compare official Italian data with the corresponding estimates generated by the GBD study. This comparison is not always easy. GBD estimates of causes of death in Italy, for example, show several differences when compared with official data. These differences, however, have a reason to exist. Italy, despite being among the countries with the best current data and, specifically, the best data on causes of death, nevertheless produces about 25 percent...
IRCCS Neurologico Mediterraneo in Pozzilli joins signatories of agreement
We are happy and honored to welcome IRCCS Neurologico Mediterraneo of Pozzilli (IS) among the signatories of the collaboration agreement for the development and implementation of the Global Burden of Disease project in Italy. With IRCCS Neuromed, there are now 20 research institutions involved in the Agreement, a consolidating national network whose goal is to make the estimates generated under the Global Burden of Disease Study increasingly adherent to the Italian and global reality and...
The Lancet: one in eight deaths in 2019 associated with bacterial infections, the second leading cause of death globally
On November 21, 2022, a recent IHME paper was published in The Lancet to present the results of an analysis of the burden of antimicrobial resistance (AMR) and bacterial pathogens and its impact on health globally. The work is part of a global initiative, Global Research on Antimicrobial Resistance (GRAM) project - implemented in collaboration with the University of Oxford - that brings together researchers from around the world to develop the evidence base for understanding the threat of...